DOSING SCHEDULE

Acute systemic toxicity includes a single exposure with a 72-hour observation period and is most commonly performed. Repeat or continuous exposure, classified as subacute, chronic, & subchronic  are also available.

ADMINISTRATION  ROUTE

Choose a route of exposure, recommended to be based on clinical relevance. Routes including oral, subcutaneous, & intravenous are available.  See a complete list of routes at STUDY DESIGNS.

STUDY ENDPOINTS

Toxicity studies can determine Maximum Tolerated Dose (MTD), No Observable Effect Level (NOEL),  & Optimal Dosing Schedule